Curriculum Vitae

Mark D. Nathan, M.D.

Dr. Nathan completed his B.S., M.S. and M.D. at Brown University. He received his cardiology training at Cedars-Sinai in Los Angeles. Dr. Nathan also holds an M.P.A. in Health Care Administration from the University of San Francisco. He conducted pioneering research in the use of ACE inhibitors in congestive heart failure and in thrombolytic therapy for acute myocardial infarction, and established the first office-based nuclear cardiology laboratory in Northern California.

Work Address: 106 La Casa Via, Suite 140 Walnut Creek, California 94598
Work Phone: Voice 925-274-2860 Fax 925-932-4527
Work Email: mnathan@ccmedgroup.com Home Email: mark@thenathans.org

Licensure:

California Medical License No. G35395, 1977
Hawaii Medical License No. 9462, 1996
Qualified Medical Examiner, Workers' Compensation, California, No. 903413, 1989
Qualified Reviewer, Medical Board of California, 1996
X-Ray Supervisor and Operator Certificate No. 118253
DEA No. AN9360676

Board Certification:

National Board of Medical Examiners, Parts I (1974), II (1976), III (1977)
American Board of Internal Medicine, 1979
ABIM, Cardiovascular Diseases Subspecialty, 1981
American Board of Utilization Review and Quality Assurance, 1996
Certification Board in Nuclear Cardiology, 2000
National Board of Echocardiography, 2003

Formal Education:

B.S., Biology, magna cum laude; Brown University, Providence, R.I., 1973
M.S., Physiological Chemistry; Brown University, 1976
M.P.A., Health Care Administration; University of San Francisco, 1997
M.D., Brown University, 1976

Clinical Training:

Internship, internal medicine; Harbor-UCLA Medical Center, Torrance, CA, 1976-77
Residency, internal medicine; Harbor-UCLA Medical Center, Torrance, CA, 1977-79
Fellowship, cardiology; Cedars-Sinai Medical Center, Los Angeles, CA, 1979-1982

Fellowships:

American College of Cardiology, 1983
American College of Physicians, 1986

Honors and Awards:

National Merit Scholar Semifinalist, 1969
B.S., magna cum laude, 1973
Sigma Xi honor society, 1973
AMA Physicians Recognition Awards, 1980-1995

Professional Societies:

Alameda-Contra Costa Medical Association
American College of Cardiology
American College of Physicians
American College of Physician Executives
American Heart Association
American Society of Internal Medicine
Brown Medical Association
California Medical Association
California Society of Internal Medicine
International Association of Medical Specialists

Academic Positions:

Research Fellowship, physiological chemistry; Brown University, 1972-1974
NIH Clinical Research Fellowship, cardiology; Cedars-Sinai Medical Center, 1980-81
Cardiac Catheterization Fellow; Cedars-Sinai Medical Center, 1981
Asst Clinical Professor of Medicine/Cardiology; Univ. of California, Davis, 1982-1986
Attending Cardiologist; VA Medical Center, Martinez, California, 1982-1986

Medical Staff Positions:

At San Ramon Regional Medical Center, San Ramon, California:
Chief of Medical Staff, 1991
Chairman, Department of Internal Medicine, 1990
Chairman, Cardiopulmonary Division, 1993-present
Chairman, Credentials Committee, 1992-1994
Representative, Hospital Medical Staff Section ,California Medical Assn, 1991-94

At John Muir Medical Center, Walnut Creek, California:
Chairman, Cardiology Section, 1995-1996
Chairman, Noninvasive Cardiology Subsection, 1990-1995
Chairman, Nuclear Cardiology Subsection, 1989-1993
Member, Institutional Review Board, 1992-1995, 2003-present
Member, Pharmacy and Therapeutics Committee, 1994-present
Member, Information Systems Advisory Committee, John Muir/Mt. Diablo Health System

Managed Care Experience:

Governing Board, San Ramon Regional Medical Center, 1990-1996
Local Quality Improvement Committee, United HealthCare of Northern California
Quality Improvement Committee, Golden State Health Network
Physician Advisor, CIGNA HealthCare of Northern California
Physician Advisory Committee, Community Care Network, Inc.
Board of Directors, Central East Bay IPA Medical Group, Inc., Walnut Creek, CA Finance, Compensation, and Utilization Management Committees, C.E.B. IPA
Utilization Management and Finance Committees of John Muir Health Network

Medical Practice and Additional Work Experience:

Founder and partner, Cardiac Consultants Medical Group, Danville, CA, 1982-1998
Partner, Cardiovascular Consultants Medical Group, Oakland, CA, 1998-present
Nuclear medicine technologist; Lutheran General Hospital, Park Ridge, ILL,1969-71
Lecturer, cardiology evaluations; Federal Aviation Administration, 1989-present
Medicolegal, State Disability, and Workers' Compensation Evaluations

Hospital Affiliations:

John Muir Medical Center, Walnut Creek, California (active)
San Ramon Regional Medical Center, San Ramon, California (active)
Mount Diablo Hospital and Medical Center, Concord, California (courtesy)
Valleycare Medical Center, Pleasanton, California (courtesy)

Research Trials:

Principal Investigator
Sportif V – melagatran in atrial fibrillation, phase III
Meteor – tolvaptan in chronic heart failure, phase II
Vision – bidenodesine in perfusion imaging, phase I
Everest – tolvaptan in chronic heart failure, phase III
Enable – bosentan in chronic heart failure, phase II

Co-investigator
Swing – therapeutic intracoronary ultrasound, native vessels, phase I
Splash – therapeutic intracoronary ultrasound, in-stent restenosis, phase I
Watch – aspirin vs. coumadin in chronic heart failure, phase IV
Attest – pacemaker therapy for atrial arrythmias, phase III
Glideline – 6 French bipolar pacemaker lead, phase I

Publications:

Articles:

Butcher, FR, Goldman, JAN, & Nathan, M (1975). Effect of adrenergic agents on alpha amylase release and adenosine 3',5'-cyclic monophosphate accumulation in rat parotid tissue slices. Biochimica et Biophysica Acta 392:82-94
Butcher, FR, Rudich, L, Emler, C, and Nathan, M (1976). Adrenergic regulation of cyclic nucleotide levels, amylase release, and potassium efflux in rat parotid gland. Molecular Pharmacology 12:862-870.
Nathan M and Shah PK (1981). Syndrome of severe bradycardia and hypotension following sublingual nitroglycerin administration. Cardiology 67: 180-189.
Nathan M and Shell, WE (1981). Prostaglandin E1 therapy in unstable angina pectoris. Prostaglandins in cardiovascular and thrombotic disorders. Pantothox Press, Chicago.
Nathan M, Shah PK, Pichler M, Berman DS, Shellock F, and Swan HJC (1982). Radionuclide assessment of sequential changes in left and right ventricular function following first acute transmural myocardial infarction. American Heart Journal 104: 709-717.
Nathan M, Rubin SA, Siemienczuk D, and Swan HJC (1982). Effects of acute and chronic minoxidil administration on rest and exercise hemodynamics and clinical status in patients with severe, chronic heart failure. Am J Cardiology 50:973-966.
Rubin SA, Siemienczuk D, Nathan M, Prause J, and Swan HJC (1982). Accuracy of cardiac output, oxygen uptake, and arteriovenous oxygen difference at rest, during exercise, and after vasodilator therapy in patients with severe, chronic heart failure. Am J Cardiology 50:973-978.
Cannon PJ et al (1983). A placebo-controlled trail of captopril in refractory chronic congestive heart failure. J Am College Cardiology 2(4):755-763.
Siegel RJ and Nathan M (1984). Prostaglandin E1 infusion in unstable angina: effects on anginal frequency and cardiac function. Amer Heart Journal 108:863-868.

Abstracts:

Butcher FR and Nathan M (1973). Effect of alpha- and beta-adrenergic stimulation on cyclic AMP levels and alpha-amylase release from rat parotid tissue slices. Federation Proceedings 32:535.
Butcher FR, Nathan M, McBride PA, and Rudich L (1974). Interaction of adrenergic and cholinergic agonists on cyclic AMP and cyclic GMP accumulation, alpha-amylase release, and potassium efflux from rat parotid tissue slices. Second International Conference on Cyclic AMP. Vancouver, p. 49.
Nathan M (1974). The effects of adrenergic agents on cyclic AMP accumulation and alpha-amylase release in rat parotid tissue slices. Brown University Senior Research Seminar. Providence, Rhode Island.
Shah PK, Nathan M, Pichler M, Berman D, and Swan HJC (1980). Early sequential changes in global and regional left ventricular function following acute myocardial infarction and their relationship to short-term prognosis. Clinical Research 28(2): 211a.
Nathan M, Rubin SA, Shah PK, Siemienczuk D, and Swan HJC (1981). Salutary hemodynamic effects of short-term minoxidil administration at rest and exercise in patients with severe chronic heart failure. Clinical Research 29:226a.
Nathan M, Shell WE, Forrester JS, and Swan HJC (1981). Measurement of inactive creatine kinase B protein in acute ischemic syndromes: Identification of a high-risk cohort. Clinical Research 29:226a.
Nathan M, Rubin SA, Brown H, Mickle D, and Swan HJC (1981). Enhanced oxyhemoglobin dissociation contributes to unloading oxygen at rest and during exercise in severe chronic heart failure patients. Am J Cardiology 47:468a.
Rubin SA, Nathan M, Brown HV, Siemienczuk D, and Swan HJC (1981). Mechanisms of dyspnea on exertion in severe, chronic heart failure. Clinical Research 29:237a.

Personal Data: Married. Two sons. Hobbies: Ice hockey, skiing, polo, hot air ballooning.

References: on request